Plasma amino acids
Definition
血浆氨基酸是一种筛选试验，通常在婴儿身上进行，检查血浆中氨基酸的含量
Alternative Names
Amino acids blood test
如何执行测试
Most of the time, 血液是从位于肘部内侧或手背的静脉抽取的.
在婴儿或幼儿中，一种叫做刺针的锋利工具可以用来刺穿皮肤.
- 血液收集在一个叫做移液管的小玻璃管中，或者收集在载玻片或试纸上.
- 在伤口上缠上绷带止血.
血液样本被送到实验室. 有几种方法用于测定血液中单个氨基酸的水平.
如何准备考试
接受检查的人可能会被要求在检查前3小时或更长时间内不要进食. 向孩子的医疗保健提供者咨询具体建议.
How the Test will Feel
当针插入时，可能会有轻微的疼痛或刺痛. 抽血后，您可能还会在该部位感到一些悸动. 针头可能会导致婴儿或儿童哭泣.
为什么要进行测试
这个测试是用来测量血液中氨基酸的含量.
一种特定氨基酸水平的增加表明身体分解(代谢)这种氨基酸的能力出了问题.
该测试也可用于寻找血液中氨基酸水平的降低.
发烧时血液中氨基酸水平升高或降低, inadequate nutrition, 以及某些医疗十大赌博靠谱网络平台.
Normal Results
所有测量单位为微摩尔/升(µmol/L). 不同实验室的正常值可能不同. 与你的医疗保健提供者谈谈你的具体测试结果.
Alanine:
- Children: 200 to 450
- Adults: 230 to 510
Alpha-aminoadipic酸:
- Children: not detected
- Adults: not detected
Alpha-amino-N-butyric酸:
- Children: 8 to 37
- Adults: 15 to 41
Arginine:
- Children: 44 to 120
- Adults: 13 to 64
Asparagine:
- Children: 15 to 40
- Adults: 45 to 130
Aspartic acid:
- Children: 0 to 26
- Adults: 0 to 6
Beta-alanine:
- Children: 0 to 49
- Adults: 0 to 29
Beta-amino-isobutyric酸:
- Children: not detected
- Adults: not detected
Carnosine:
- Children: not detected
- Adults: not detected
Citrulline:
- Children: 16 to 32
- Adults: 16 to 55
Cystine:
- Children: 19 to 47
- Adults: 30 to 65
Glutamic acid:
- Children: 32 to 140
- Adults: 18 to 98
Glutamine:
- Children: 420 to 730
- Adults: 390 to 650
Glycine:
- Children: 110 to 240
- Adults: 170 to 330
Histidine:
- Children: 68 to 120
- Adults: 26 to 120
Hydroxyproline:
- Children: 0 to 5
- Adults: not detected
Isoleucine:
- Children: 37 to 140
- Adults: 42 to 100
Leucine:
- Children: 70 to 170
- Adults: 66 to 170
Lysine:
- Children: 120 to 290
- Adults: 150 to 220
Methionine:
- Children: 13 to 30
- Adults: 16 to 30
1-methylhistidine:
- Children: not detected
- Adults: not detected
3-methylhistidine:
- Children: 0 to 52
- Adults: 0 to 64
Ornithine:
- Children: 44 to 90
- Adults: 27 to 80
Phenylalanine:
- Children: 26 to 86
- Adults: 41 to 68
Phosphoserine:
- Children: 0 to 12
- Adults: 0 to 12
Phosphoethanolamine:
- Children: 0 to 12
- Adults: 0 to 55
Proline:
- Children: 130 to 290
- Adults: 110 to 360
Serine:
- Children: 93 to 150
- Adults: 56 to 140
Taurine:
- Children: 11 to 120
- Adults: 45 to 130
Threonine:
- Children: 67 to 150
- Adults: 92 to 240
Tyrosine:
- Children: 26 to 110
- Adults: 45 to 74
Valine:
- Children: 160 to 350
- Adults: 150 to 310
上面的示例显示了这些测试结果的常用度量. 一些实验室使用不同的测量方法或可能测试不同的样品.
异常结果意味着什么
血液中氨基酸总水平的增加可能是由于:
- Eclampsia
- 天生的新陈代谢错误
- Fructose intolerance
- 酮症酸中毒(糖尿病)
- Kidney failure
- Reye syndrome
- Laboratory error
血液中氨基酸总水平的下降可能是由于:
- 肾上腺皮质功能亢进
- Fever
- Hartnup disease
- 天生的新陈代谢错误
- Huntington chorea
- Malnutrition
- Nephrotic syndrome
- Phlebotomus fever
- Rheumatoid arthritis
- Laboratory error
个体血浆氨基酸的高或低量必须与其他信息一起考虑. 异常结果可能是由于饮食、遗传问题或药物的作用.
Considerations
对婴儿进行氨基酸水平增加的筛查有助于发现新陈代谢问题. 对这些疾病的早期治疗可以预防未来的并发症.
References
Dietzen DJ, Vieira Willrich MA. 氨基酸、多肽和蛋白质. In: Rifai N, Chiu RWK, Young I, Burnham C-A D, Wittwer CT，编. Tietz检验医学教科书. 7th ed. St Louis, MO: Elsevier; 2023:chap 31.
Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM. 氨基酸代谢缺陷. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM，编. 纳尔逊儿科学教材. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 103.
Riley RS, McPherson RA. 尿液基本检查. 见:McPherson RA, Pincus MR，编辑. 亨利氏病的临床诊断及实验室方法处理. 24th ed. Elsevier; 2022:chap 29.
Review Date: 04/24/2023